Scientific validation

Clinical practice guidelines

Toward Clinically Feasible Assessment of Muscle Mass: Validation of a Seated Bioelectrical Impedance Device Against Dual-Energy X-Ray Absorptiometry (DXA) in Older Adults

Validation study of the seated Biody Xpert ZM 3 bioelectrical impedance analysis (BIA) device compared to DXA (Dual-energy X-ray Absorptiometry) for measuring appendicular skeletal muscle mass (ASMM) in older adults. The study evaluated two predictive equations (Kyle and Sergi) and examined associations between phase angle (PhA) and physical performance. Results demonstrate that the population-specific Sergi equation offers superior accuracy, with higher concordance and lower systematic bias than the Kyle equation, while PhA positively correlates with handgrip strength.

→ Supports seated BIA as a practical, clinically acceptable alternative to DXA for routine muscle mass and quality assessment in geriatric populations.

Intra-rater reliability and agreement of a portable bioelectrical impedance analysis device for body composition assessment

Scientific validation

Validation study of the Biody Xpert ZM III compared to DXA (Dual-energy X-ray Absorptiometry), conducted in both sitting and supine positions. Results demonstrate excellent agreement, with a mean deviation of approximately 3.7 Ω on impedance measurements and less than 1% difference on fat mass assessment. No statistically significant differences were observed for fat mass, lean mass, or fat-free mass.

→ Confirms accuracy and reliability equivalent to the DXA reference standard.

Reproducibility of Bioimpedance Spectroscopy Parameters to Evaluate Skeletal Muscle Properties

Muscle, Scientific validation

Study evaluating the reproducibility of Spectroscopic Bioimpedance (BIS) parameters for characterizing skeletal muscle properties. Results demonstrate good measurement stability and sensitivity to variations in muscle length and circumference, suggesting the capacity to detect structural and functional alterations.

→ A relevant tool for monitoring muscle disorders and supporting rehabilitation protocols.

Publication	Title	Category
González-Correa, C. A., S. A. Jaimes, et J. I. Cárdenas-Jiménez. « Preliminary Study on Parameterization of Raw Electrical Bioimpedance Data with 3 Frequencies ». Scientific Reports 12, no 1 (3 juin 2022): 9292. https://doi.org/10.1038/s41598-022-13299-7	Preliminary Study on Parameterization of Raw Electrical Bioimpedance Data with 3 Frequencies	Scientific validation
Charatsi, A. M., P. Dusser, R. Freund, G. Maruani, H. Rossin, A. Boulier, M. Le Bourgeois, et al. « Bioelectrical Impedance in Young Patients with Cystic Fibrosis: Validation of a Specific Equation and Clinical Relevance ». Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society 15, no 6 (novembre 2016): 825-33. https://doi.org/10.1016/j.jcf.2016.05.004	Bioelectrical Impedance in Young Patients with Cystic Fibrosis: Validation of a Specific Equation and Clinical Relevance	Scientific validation